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系统生物学导论 Introduction to systems biology
关键字：系统生物学导论 Introduction to systems biology|系统生物学导论 Introduction to systems biology培训|系统生物学导论 Introducti
学校价格：￥来电咨询 网上优惠价：￥团购享优惠 关注度：532人 
总课时：预约咨询 开班日期：滚动开班 上课时段：平日班|晚班|周末班 授课学校：北京爱预科教育 上课地点：北京市海淀区清华东路 课程介绍This course will introduce the student to contemporary Systems Biology focused on mammalian cells, their constituents and their functions. Biology is moving from molecular to modular. As our knowledge of our genome and gene expression deepens and we develop lists of molecules (proteins, lipids, ions) involved in cellular processes, we need to understand how these molecules interact with each other to form modules that act as discrete functional systems. These systems underlie core subcellular processes such as signal transduction, transcription, motility and electrical excitability. In turn these processes come together to exhibit cellular behaviors such as secretion, proliferation and action potentials. What are the properties of such subcellular and cellular systems? What are the mechanisms by which emergent behaviors of systems arise? What types of experiments inform systems-level thinking? Why do we need computation and simulations to understand these systems? The course will develop multiple lines of reasoning to answer the questions listed above. Two major reasoning threads are: the design, execution and interpretation of multivariable experiments that produce large data sets; quantitative reasoning, models and simulations. Examples will be discussed to demonstrate “how” cell- level functions arise and “why” mechanistic knowledge allows us to predict cellular behaviors leading to disease states and drug responses.
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